BioWasm Compile
Teaches Claude to compile bioinformatics tools to WebAssembly, from minimap2 to samtools.
About
BioWasm Compile is a single focused skill from the GenomicX project that guides Claude through compiling bioinformatics tools to WebAssembly with Emscripten. It encodes real-world patterns from 40+ biowasm tools: SIMD optimization for minimap2, autoconf handling for samtools and bcftools, assembly instruction fixes for bowtie2, zlib linking fixes for fastp, and ASYNCIFY for async operations. The skill ships as a .skill archive installable into ~/.claude/skills/ and includes tool-specific debugging references. The goal is browser-native bioinformatics with no installs and no uploads.
This is a niche, single-purpose skill from a 1-star repo, so set expectations accordingly: it documents build patterns, it doesn't guarantee any given tool will compile cleanly to WASM. Emscripten builds of large C/C++ bioinformatics tools remain fiddly, and the skill is a guide through that fiddliness, not a way around it.
What it can do
- Emscripten build patterns for 40+ bioinformatics tools
- Tool-specific compile and debug references
- Dependency compilation (htslib, zlib, boost)
- Memory and ASYNCIFY configuration guidance
- SKESA-specific compile notes and JS integration
Setup
Download the .skill file from the repo's releases page and extract with unzip biowasm-compile.skill -d ~/.claude/skills/. Or clone and copy: git clone https://github.com/genomicx/claude_skill.git /tmp/claude_skill, then cp -r /tmp/claude_skill/biowasm-compile/biowasm-compile ~/.claude/skills/. Invoke with /biowasm-compile minimap2.
Prerequisites
Claude Code; Emscripten toolchain for actual compilation work.
Use cases
Works with
Trust score — 6/10
Scored 6/10 (metrics tier, metrics-v1). Evidence: 1 GitHub star, MIT license per README, single focused skill; Concrete install via .skill archive unzip or git clone + cp; Real patterns from 40+ biowasm tools documented; Caveat: niche single-purpose skill; Emscripten builds remain fiddly regardless.
★ 1 GitHub stars
Sources
Every fact above was checked against these sources. Where a claim comes from the provider and couldn't be independently verified, the text says so.